Patients treated for hepatitis C who achieved sustained virologic response recovered platelet counts, according to recently published data. Hepatitis B coinfection, however, disrupted platelet count recovery, especially in patients with advanced liver disease from chronic HCV.
“Taken collectively, it is postulated that the factors associated with [platelet] recovery may be linked to fibrotic regression,” the researchers wrote. “Interestingly, we noticed that HBV co-infection was associated with slow [platelet] recovery. The result hints that HBV co-infection may interfere with fibrotic regression in patients with curative HCV infection.”
Of particular note was that the condition existed only in patients with advanced liver disease.