Friday, June 22, 2018

News Recap:

All Kids Should Have a Hepatitis B Shot. Clinicians and researchers attending an international conference say all Canadian children should be vaccinated against hepatitis B starting at birth to prevent the development of potentially deadly liver disease later in life, a policy recommended by the World Health Organization. Currently, most provinces and territories immunize children against the liver-destroying virus when they are much older.

At Large:
Researchers Find a Promising New Approach for Treating Liver Cirrhosis. In a study in The American Journal of Pathology, investigators report that treatment with aleglitazar, a dual peroxisome proliferator-activated receptor-alpha/gamma (PPARα/γ) agonist, reduced inflammation, vasoconstriction, angiogenesis, mucosal disruption, and tumor necrosis factor (TNF)-α overproduction in cirrhotic rats with PH. This suggests a promising new approach for treating liver cirrhosis.

Switching to Tenofovir vs Continuing Entecavir in Chronic Hepatitis B. Switching to tenofovir disoproxil fumarate (TDF) is more efficacious than continuing entecavir (ETV) for achieving an optimal response in patients with chronic hepatitis B with a partial virologic response to ETV, according to a multicenter, open-label, randomized controlled study published in the Journal of Viral Hepatitis.