Insulin Resistance in HCV May Be Reversed With DAAs

Hepatitis C (HCV) is associated with insulin resistance, and elimination of the virus may help re-establish glycemic control in affected patients, according to a prospective case-control study published in the Journal of Gastroenterology and Hepatology. Approximately 76.5% of patients who achieved a sustained virologic response experienced improvements in insulin resistance. There was a significant 2.42±1.85 point reduction in insulin resistance as assess

Men who have sex with men urged to get tested for hepatitis A after another outbreak

Why exactly should people in Europe and the US get tested? Since the Europe-wide outbreak began in June 2016, 3,813 cases of hepatitis A have been confirmed, and the European Centre of Disease Control is urging people to get tested. “As of December 18 2017, the monthly number of laboratory-confirmed cases remain significantly higher than in previous years,” the ECDC told The Express. “Although decreasing in its intensity, the outbreak is still ongoi

Hepatitis B Vaccination Low Among HIV-Positive Patients

Patients with HIV are at an increased risk of numerous comorbidities and infections, including hepatitis B virus (HBV). Due to the opioid epidemic, injection drug users have a significantly increased risk of contracting HBV and hepatitis C virus, especially those coinfected with HIV. Recently, the American College of Physicians and CDC released new best practice guidelines to address HBV. The guidelines stress that all adults, including at-risk pregnant w

NASH, HCV cirrhosis predict coronary artery disease in liver transplantation

Patients who underwent liver transplantation evaluation had a high prevalence of coronary artery disease, especially those with nonalcoholic steatohepatitis-related cirrhosis, hepatitis C-related cirrhosis and alcoholic cirrhosis, according to a recently published study. An integral component of the liver transplant evaluation (LTE) is coronary artery disease (CAD) assessment as surgical morbidity and mortality can be as high as 81% and 50%, respectively,

Smoking reduces survival after liver cancer diagnosis for people with viral hepatitis

People with viral hepatitis who smoked were three times more likely to die after being diagnosed with liver cancer (hepatocellular carcinoma, HCC), according to a study of Swiss patients published in Liver International. Whereas non-smokers lived for a median of 3.2 years after diagnosis, smokers died after a median of 18 months. Smoking had a similar impact on survival in those who did not receive curative treatment in the form of liver resection (surger

The Week in Review: January 5 – January 12, 2018

Friday, January 12, 2018 News Recap: Officials warn customers of London, Ont., nail salon to get tested for HIV, hepatitis B, C. The Middlesex-London Health Unit issued an alert warning clients of Cali Nails in the White Oaks Mall that they should talk to their doctors. A customer who contracted hepatitis B went to the salon for a manicure and pedicure. The advisory is for anyone who visited the salon between May 4, 2017, and Jan. 5, 2018. Dynavax...

Officials warn customers of London, Ont., nail salon to get tested for HIV, hepatitis B, C

The Middlesex-London Health Unit issued an alert Wednesday warning clients of Cali Nails in the White Oaks Mall that they should talk to their doctors. Mary Lou Albanese, the manager of the health unit’s infectious disease control team, says a customer who contracted hepatitis B went to the salon for a manicure and pedicure. She says her agency is issuing the advisory for anyone who visited the salon between May 4, 2017, and Jan. 5, 2018. Albanese a

Dynavax Announces HEPLISAV-B™ is Now Available in the United States for the Prevention of Hepatitis B in Adults

HEPLISAV-B is the First and Only Two-Dose Vaccine in U.S. for Hepatitis B Prevention in Adults BERKELEY, Calif., Jan. 08, 2018 (GLOBE NEWSWIRE) -- Dynavax Technologies Corporation (NASDAQ:DVAX) today announced that HEPLISAV-B™ [Hepatitis B Vaccine (Recombinant), Adjuvanted] is now available in the United States for the prevention of infection caused by all known subtypes of hepatitis B virus in adults age 18 years and older. HEPLISAV-B was approved

Brief: HCV spread from HIV-positive to HIV-negative men who have sex with men

Brief: The aim of this study was to evaluate the potential transmission of HCV strains between HIV-positive men who have sex with men (MSM) and HIV-negative MSM.  Chronological analysis of contagiousness suggested the transmission of HCV from HIV-positive to HIV-negative patients. We conclude that recommendations for HCV surveillance should not be confined to HIV-positive MSM but should be extended to HIV-negative MSM with similar risk factors. PLoS One

Brief: Outcome of HBV and HCV associated HCC occurring after renal transplantation.

Brief: Survival after HCC diagnosis is significantly worse in KTR compared to nontransplanted patients with HBV and/or HCV. Prevention is crucial and should be based on viral eradication/suppression before or after transplantation. PLoS One. 2018 Jan 2;13(1):e0190340. doi: 10.1371/journal.pone.0190340. eCollection 2018. https://www.ncbi.nlm.nih.gov/pubmed/27917563