The Week in Review: June 22 – June 29, 2018

Friday, June 29, 2018 News Recap: Canada: Boomer Moms At High Risk For Hep C, Says Doctor. A quarter million Canadians are believed to have the hepatitis C virus at this moment, and many have no idea. Dr. Rod Russell says it’s really baby boomers at the highest risk, and to be specific, it’s our mothers, the women who gave birth before 1992, especially if they had blood transfusions during pregnancy. Their children are also at risk because if the mo...

DAA Therapy Highly Efficacious for HCV Treatment in Older Adults

Direct-acting antiviral (DAA) therapy is highly efficacious for the treatment of hepatitis C virus (HCV) infection in individuals >65 years; however, those 75 years are more likely to be at risk for significant drug-drug interactions and experience adverse events during therapy, according to a retrospective study published in the Journal of the American Geriatrics Society. Sustained virologic response rate was 97.7% in individuals aged 65 to 74 years a

Boomer Moms At High Risk For Hep C, Says Doctor

A quarter million Canadians are believed to have the hepatitis C virus at this moment, and many have no idea. Dr. Rod Russell says HCV is a long progression, and you don’t normally see liver disease or cirrhosis until years 15 or 20 into the infection. He says treating the infection early can prevent damage to the liver earlier but there is still a problem. Russel says it’s really baby boomers at the highest risk, and to be specific, it’s our mothers,

Health unit urges dental patients to get tested after child revealed to have hepatitis C

ORILLIA, Ont. -- A central Ontario dentist is defending his practice after public health officials said two patients who had received dental services at his clinic tested positive for hepatitis C. Simcoe Muskoka District Health Unit confirmed a child is one of two individuals who tested positive for Hepatitis C after receiving dental care at Joe Philip and Associates dental office between Jan. 1, 2012 and Dec. 18, 2017. SMDHU first made a recommendatio

NZ: Campaign to be first to wipe out hepatitis C

About 700 people in Gisborne have hepatitis C. Health professionals want to make this the first region in New Zealand to eradicate hepatitis C from the community. Next week sees the launch of a hep C eradication campaign. About 700 people have hepatitis C here. It is estimated only half know they have the virus. These people are in their 40s and 50s (60 percent male) and have either injected drugs (in some cases, just once) had a tattoo or a blood tran

Liver highlights from DDW 2018

Below are some of the hepatology highlights from DDW 2018 presented by Healio Homeless veterans with HCV diagnosed, treated via PCP outreach Plasma assay of methylated DNA markers detects liver cancer across all stages HCV outcomes worse for patients with public insurance, Medicaid Exclusion from HBV therapy by AASLD criteria often leads to adverse outcomes Read more...https://www.healio.com/hepatology/steatohepatitis-metabolic-liver-disea...

The Week in Review: June 15 – June 22, 2018

Friday, June 22, 2018 News Recap: Canada: All Kids Should Have a Hepatitis B Shot. Clinicians and researchers attending an international conference say all Canadian children should be vaccinated against hepatitis B starting at birth to prevent the development of potentially deadly liver disease later in life, a policy recommended by the World Health Organization. Currently, most provinces and territories immunize children against the liver-destroyin...

Researchers find a promising new approach for treating liver cirrhosis

A study in The American Journal of Pathology, investigators report that treatment with aleglitazar, a dual peroxisome proliferator-activated receptor-alpha/gamma (PPARα/γ) agonist, reduced inflammation, vasoconstriction, angiogenesis, mucosal disruption, and tumor necrosis factor (TNF)-α overproduction in cirrhotic rats with PH. This suggests a promising new approach for treating liver cirrhosis. Increased pressure in the veins leading to the liver, known

All Kids Should Have a Hepatitis B Shot

TORONTO — Clinicians and researchers attending an international conference say all Canadian children should be vaccinated against hepatitis B starting at birth to prevent the development of potentially deadly liver disease later in life, a policy recommended by the World Health Organization. Currently, most provinces and territories immunize children against the liver−destroying virus when they are much older, including Ontario and Nova Scotia, which sugg

Switching to Tenofovir vs Continuing Entecavir in Chronic Hepatitis B

Switching to tenofovir disoproxil fumarate (TDF) is more efficacious than continuing entecavir (ETV) for achieving an optimal response in patients with chronic hepatitis B with a partial virologic response to ETV, according to a multicenter, open-label, randomized controlled study published in the Journal of Viral Hepatitis. No studies have directly compared the efficacy of switching from ETV to TDF with that of continuing ETV; therefore, researchers pros