PATIENT GROUP SUBMISSIONS to BC PharmaCare, CADTH, & PMPRB

PATIENT GROUP SUBMISSIONS to BC PharmaCare, CADTH, & PMPRB Whenever we are asked to contribute a patient group submission about a hepatitis-C or hepatitis-B related product, we do so. We contribute as a patient group to reviews by both BC PharmaCare (to determine whether BC PharmaCare patients will be reimbursed for the drugs) and CADTH (federal level – to determine whether the drugs will be available in Canada). Occasionally we also submit patien

Current Treatments

Current HCV Treatments in BC as of March 2019 IMPORTANT: As of March 13, 2018,  anyone in B.C. living with this now-curable virus will have a choice of several treatment options – all of which are fully funded under BC PharmaCare, and all restrictions based on disease level have been removed. There are many drug combinations available for treating hepatitis C in Canada which are also covered by BC Pharmacare.  Older combinations involved the use of i

FDA Approves Expanded Use of Daklinza (daclatasvir) for Additional Challenging-to-treat Patients with Genotype 1 or Genotype 3 Chronic Hepatitis C

Updated label provides new treatment option for patients with HIV-1 coinfection, advanced cirrhosis, and post-liver transplant HCV recurrenceFriday, February 5, 2016 12:47 pm EST--PRINCETON, N.J.--(BUSINESS WIRE)--Bristol-Myers Squibb Company (NYSE:BMY) announced today that Daklinza™ (daclatasvir, 60 mg), an NS5A replication complex inhibitor, has been approved by the U.S. Food and Drug Administration (FDA) in combination with sofosbuvir (with or without r

The Medicines Patent Pool Signs First Sub-licences for Hepatitis C Medicine Daclatasvir

GENEVA, January 20, 2016 /PRNewswire/ --Four companies to help speed access to curative direct-acting antiviral in 112 low- and middle-income countries The Medicines Patent Pool (MPP) announced its first round of sub-licences for the generic production of Bristol-Myers Squibb's daclatasvir, a novel direct-acting antiviral that is proven to help cure multiple genotypes of the hepatitis C virus. Generic companies Cipla, Emcure, Hetero and Natco have signed n

AASLD 2015 Update: Hepatitis C Still Focus of Liver Meeting

SAN FRANCISCO — The latest trials of combination hepatitis C drugs aimed at specific genotypes will get top billing at this year's Liver Meeting."We have seen phenomenal change in hepatitis C treatment over the last 2 years, and this has not slowed down one bit," said Gary Davis, MD, from MedLogician Consulting in Simpsonville, South Carolina, who is cochair of the American Association for the Study of Liver Diseases scientific program committee.For the di

Summer of Interferon-free Hepatitis C Drug Approvals?

2015 is stacking up to have a Summer of Interferon-Free hepatitis C drug approvals! So far we've had the following approvals for provincial Pharmacare coverage (addition to provincial "formulary"):On June 29th, Ontario covered AbbVie's Holkira Pak™ for genotype 1, on July 24th, Quebec covered both Gilead's Harvoni™ and AbbVie's Holkira Pak™ for genotype 1. And on World Hepatitis Day, July 28th British Columbia, Saskatchewan, Manitoba, and Yukon started to ...

Updated: HepCBC Patient Group Submissions to CADTH and BC Pharmacare

To view all submissions (2011 to present) HepCBC has made to either CADTH (to determine if drug should be allowed for sale in Canada for a specific purpose) and BC Pharmacare (to determine if drug should be covered/purchase reimbursed by Pharmacare) please see this updated link: http://hepcbc.ca/patient-group-submissions-bc-pharmacare-cadth/

Bristol-Myers Squibb’s “Stand-Alone” marketing of daclatasvir worldwide refreshing change

Amadou Diarra, Bristol-Myers Squibb Vice President, Global Policy & Government Affairs, source BMS website We recently praised the Bristol-Myers Squibb (BMS) marketing of daclatasvir as a 'stand-alone' hepatitis C drug which could be easily marketed and combined with other drugs instead of being packaged only with other drugs from the same company in a proprietary "package" (http://hepcbc.ca/2014/10/praise-stand-alone-hcv-drugs/). When our goal is th

In Praise of Stand-Alone HCV Drugs

BMS recently withdrew its US FDA application for the hepatitis C drug, asunaprevir. It is probably a very wise decision on BMS' part, because asunaprevir is close in formulation and results to several other generation 2 NS3 protease inhibitors*. Instead, BMS seems to be focusing on its more unique product, the NS5A replication complex inhibitor, daclatasvir, of which they say in their Oct. 7 press release, is "currently being investigated globally in multi