Liver test to aid paracetamol overdose treatment

People who overdose on paracetamol (acetaminophen) could be helped by a blood test that shows immediately if they are going to suffer liver damage. Researchers in Edinburgh and Liverpool said the test would help doctors identify which patients arriving in hospital need more intensive treatment. The blood test detects levels of specific molecules in blood associated with liver damage. The three different molecules are called miR-122, HMGB1 and FL-K18

Singapore’s Restalyst develops new method to improve liver cancer diagnosis

SINGAPORE, Nov. 9, 2017 /PRNewswire/ -- Singapore biomedical firm Restalyst has developed a new algorithm to detect liver cancer more accurately, improving the sensitivity to 90%. The new methodology looks at three factors: membrane bound protein ERBB3, AFP (alpha fetoprotein) and age of patient. It will detect and identify liver cancer more effectively, and better distinguish liver cancer from chronic hepatitis condition. An AFP test is commonly used

The Week in Review: October 6 – October 13, 2017

Friday, October 13, 2017 News Recap: Research & Discoveries After an intense hunt, researchers at the Norwegian University of Science and Technology (NTNU) can now describe an important part of the disease's guerrilla tactics: how hepatitis C converts innocent cells into outright virus factories.  How hepatitis C hides in the body. Apparently, liver cancer can be caught at an early stage through a newly developed blood test, improving the odd...

Blood test may find liver cancer earlier, improve survival

Liver cancer can be caught at an early stage through a newly developed blood test, improving the odds for survival, according to a study led by University of California San Diego scientists. The test looks for changed gene activity, caused by a process called methylation, that indicate liver cancer, said Kang Zhang, M.D., the study’s senior author. Methylation turns genes on or off, but doesn’t affect the underlying DNA sequence. Early detection is imp

The Week in Review: August 4 – August 11, 2017

Friday, August 11, 2017 Research & Discoveries Melbourne scientists are creating mini-livers in a dish MELBOURNE scientists are creating mini livers in a dish using a world-first combination of human cells in an ambitious bid to grow liver tissue for transplants. The tiny experimental organs – developed from cells donated by cancer patients – will be used to test drugs and eventually treat disease. Routine hospital tool found to predict poor ...

Routine hospital tool found to predict poor outcomes after liver transplantation

Findings of research led by Cedars-Sinai may help pinpoint liver transplant recipients at risk for early disability and prolonged hospitalization LOS ANGELES (Aug. 10, 2017) -- A routinely used hospital tool can predict which liver transplant recipients are more likely to do poorly after surgery, according to a study led by Cedars-Sinai. The findings could help doctors identify which patients should receive physical therapy or other targeted interventions