The Week in Review: June 2 – June 9, 2017

Friday, June 9, 2017 News Recap Somebody Pinch Me This week saw the release of a report from the Cochrane Collaboration which concluded not only that DAAs were ineffective but that they might also be bad for you and not even cure HCV.  The news item was picked up by various media outlets and was hard to miss (No valid evidence $40,000 miracle drug cures hepatitis C – study).  Thankfully other researchers from around the world jumped in on this poor ...

Sofosbuvir Reduces Transplant Need and Mortality Rates in Hepatitis C Patients, Study Finds

Sofosbuvir (sold under the brand name Sovaldi from Gilead Sciences, among others) significantly reduces the risk of death and the need for liver transplant in patients with hepatitis C who suffer from advanced stages of liver disease. Researchers at Intermountain Healthcare’s Intermountain Medical Center in Salt Lake City studied almost 1,900 patients with hepatitis C and found that the number of patients needing a liver transplant was reduced by 40 per...

Liver cirrhosis and decompensation still on the rise among people with hepatitis C

Complications of advanced liver disease including cirrhosis and hepatic decompensation have risen over the past decade among people with chronic hepatitis C, according to study findings presented at the 2016 AASLD Liver Meeting in November. However, in recent years the increase has slowed, especially among those at highest risk – black people and people aged 60 and over. Men had significantly higher decompensation prevalence than women, though both rose a

Blood victim finally told she is free of Hepatitis C – 29 years after becoming infected

Hello Canada:  This is what happens to a person who is cured of hepatitis C after 29 years of ravaging by the virus!!  Is anyone listening?  TREAT NOW! A victim of the contaminated blood scandal has been told she is now free of Hepatitis C – 29 years after she was given a transfusion. While she has to wait another six months to ensure no traces of the disease return, Michelle Tolley, 51, from Sparham said she is now “very hopeful”. The mother of fou

Diabetes Ups Risk of HCC, Death in Patients With Hepatitis C

For hepatitis C virus-infected patients, diabetes mellitus is associated with increased risk of hepatocellular carcinoma development and all-cause mortality, according to a study published online Dec. 8 in the Journal of Gastroenterology and Hepatology. Ting-Shuo Huang, M.D., from the Chang Gung Memorial Hospital in Keelung, Taiwan, and colleagues used data from the Taiwanese National Health Insurance Research Database to evaluate the effect of DM on the

US: Large Study Identifies Increase of Cirrhosis in Hepatitis C Patients

BOSTON, Nov. 11, 2016 /PRNewswire/ -- Over the past decade, the prevalence of cirrhosis has increased by almost 40 percent among people with hepatitis C (HCV) in the United States, according to research presented at The Liver Meeting® — held by the American Association for the Study of Liver Diseases. Hepatitis C has been linked to cirrhosis (i.e., scarring of the liver), decompensated cirrhosis, and death, but the extent of the prevalence of thes...

Fibrosis in HCV genotype 3 progresses with age

Evidence of fibrosis was common in older patients with hepatitis C virus genotype 3 infection, indicating fibrosis progresses with age and this patient population should be treated as often and with the same medications as other severe HCV patient populations, according to data presented at the British Society of Gastroenterology Annual Meeting. According to Keeley Fairbrass, of the Digestive Disease Centre, Bradford Teaching Hospitals NHS Foundation Trus

Alcohol accelerates liver damage in people living with hepatitis C

More comprehensive approaches to care needed, according to a new study in the American Journal of Preventive Medicine. Ann Arbor, MI, May 10, 2016 - Drinking alcohol can increase the risk of illness and death from the hepatitis C virus. A new national household study of U.S. adults published in the American Journal of Preventive Medicine shows that many people living with hepatitis C report either former or current excessive alcohol use. In addition,

HCV-related cirrhosis prevalence increases over time

“Most patients with chronic hepatitis C infection are asymptomatic,” Kim said. “Importantly, the proportion of people with cirrhosis was the same between hepatitis C positive individuals who were aware of their infection and those who were not,” adding that chronic HCV is now curable, therefore improved outcome can be expected from a prompt screening and appropriate treatments. The rate of cirrhosis found among patients with hepatitis C virus infection in

First Canadian Study Demonstrates Potential to Remove Patients from Active Liver Transplant List After Curing Hepatitis C

- "The Days of Hepatitis C Dominating Liver Transplantation Are Numbered" - LONDON, ON, May 3, 2016 /CNW/ - Researchers with the Multi-Organ Transplant Program at London Health Sciences Centre and the Lawson Health Research Institute have been able to remove one-third (33 per cent) of patients from the active liver transplant waiting list by "curing" them of their Hepatitis C disease.  This is the first Canadian data that demonstrates the benefit of treat...