Liver Damage Worse in Women With HBV/HCV Coinfection, Risky Drinking

Coinfection with hepatitis B and C virus (HBV/HCV) combined with risky alcohol consumption enhances liver damage mechanisms to a greater extent in women than in men, according to a recent study in PLoS One. Hepatitis infection and risky drinking are major risk factors for liver disease, and coinfection with both HBV and HCV is more likely to progress to cirrhosis than single infections. Pooled data from 2 national surveys in Italy allowed the estimation o

The Week in Review: December 1 – December 8, 2017

Friday, December 8, 2017 News Recap: URGENT BC Patient and Caregiver Input Request: Vosevi. We need to hear your voice! Patient and Caregiver input is requested by BC PharmaCare on Gilead’s combo of sofosbuvir, velpatasvir, and voxilaprevir (SOF-VEL-VOX or Vosevi™) for Genotypes 1-6. Personal Stories This week we have two great stories of triumphing over HepC: Aidain’s ‘I will never forget the day I found out I had hepatitis c’, and Patric...

Hep C and me: ‘I was nauseous all the time. I couldn’t gain weight. My skin was itchy and raw’

WHEN I WAS diagnosed with Hepatitis C in the 1990s I was told I’d loads of more serious problems I had to deal with first. I remember getting the result and the doctor turning to me and saying, Patrick, it’ll kill you in 30 years so don’t worry about it. I was using drugs. I’d washed up to an addiction service, exhausted from the drugs, exhausted from the chaos of it all. I was tested. I was given advice that at the time that somehow made sense. Thirty

McGill study finds people infected with HIV more likely to develop fatty liver

Fatty liver is among the most frequent causes of liver disease in Canada and in Western countries and is one of the main indications for liver transplant. For some time, researchers have suspected that people living with HIV could be at higher risk of developing liver disease, which, as a result of longer life expectancy thanks to antiretroviral therapy, has become the major cause of their mortality in North America. Due to the invasiveness of liver biops

The Week in Review: November 4 – November 10, 2017

Friday, November 10, 2017 News Recap: Canada: Updated List of Physicians in British Columbia Currently Treating Hepatitis B and/or Hepatitis C. HepCBC has updated its list of Doctors in BC who treat HCV and HBV. Direct-Acting Antiviral Therapy Outcomes in Canadian Chronic Hepatitis C Telemedicine Patients. Many of the 300,000 HCV-infected Canadians live in under-served and remote areas without access to HCV healthcare specialists. Telemedicine (T...

HCV-related liver disease on the rise in women

Hepatitis C virus (HCV)-related complications are increasing among women, according to a national cohort study. Typically, men have a higher risk of progression to liver disease than women because men develop liver disease from HCV at a higher rate than women. “We found that women had increase of incidence of liver disease at a similar rate to men.  Since the mortality rate was lower in women, this suggests that women will have a larger contribution to t

The Week in Review: October 13 – October 20, 2017

Friday, October 20, 2017 News Recap: Disease Management: Women: Hepatitis C in pregnancy: screening, treatment, and management. Hepatitis C (HCV) during pregnancy is associated with serious, adverse outcomes. Infants born to women with HCV are more likely to experience fetal growth restriction and low birth weight. For women, chronic HCV is associated with progressive liver damage and, during pregnancy, can be transmitted from the mother to the fe...

SVR reduces hepatic venous pressure gradient, portal hypertension persists

Sustained virologic response correlated with reduced hepatic venous pressure gradient in patients with HCV-associated cirrhosis, according to a recently published study. However, clinically significant portal hypertension continued to persist in most patients. “Development of [clinically significant portal hypertension] is a hallmark in the natural history of cirrhosis because it is associated with a higher risk of hepatic decompensation, and increased ri

The Week in Review: October 6 – October 13, 2017

Friday, October 13, 2017 News Recap: Research & Discoveries After an intense hunt, researchers at the Norwegian University of Science and Technology (NTNU) can now describe an important part of the disease's guerrilla tactics: how hepatitis C converts innocent cells into outright virus factories.  How hepatitis C hides in the body. Apparently, liver cancer can be caught at an early stage through a newly developed blood test, improving the odd...

Hospice care may come too late for patients with chronic liver disease

Patients with chronic liver disease, such as nonalcoholic fatty liver disease, alcoholic liver disease and chronic hepatitis C, had significantly longer hospital length of stay, annual health care charges and shorter hospice length of stay compared with other patients, according to recently published data. “Although many experts have advocated for the expansion of hospice care to persons dying of all chronic illnesses including those patients without canc