The Week in Review: October 6 – October 13, 2017

Friday, October 13, 2017 News Recap: Research & Discoveries After an intense hunt, researchers at the Norwegian University of Science and Technology (NTNU) can now describe an important part of the disease's guerrilla tactics: how hepatitis C converts innocent cells into outright virus factories.  How hepatitis C hides in the body. Apparently, liver cancer can be caught at an early stage through a newly developed blood test, improving the odd...

How hepatitis C hides in the body

The Hepatitis C (HCV) virus is a sly enemy to have in one's body. Not only does it manage to make itself invisible to the immune system by breaking down communication between the immune cells, it also builds secret virus "factories" that quickly go into mass production. It takes one to three months from infection to disease, which in the worst case scenario can lead to liver failure and death over time. After an intense hunt, researchers at the Norwegi

Blood test may find liver cancer earlier, improve survival

Liver cancer can be caught at an early stage through a newly developed blood test, improving the odds for survival, according to a study led by University of California San Diego scientists. The test looks for changed gene activity, caused by a process called methylation, that indicate liver cancer, said Kang Zhang, M.D., the study’s senior author. Methylation turns genes on or off, but doesn’t affect the underlying DNA sequence. Early detection is imp

The Week in Review: September 22 – September 29, 2017

Friday, September 29, 2017 News Recap: Merck discontinues HCV programs. There were rumours, but now it’s official: Merck has announced that it will discontinue the development of the investigational combination regimens MK-3682B (grazoprevir/ruzasvir/uprifosbuvir) and MK-3682C (ruzasvir/uprifosbuvir) for the treatment of chronic hepatitis C virus (HCV) infection. In a statement the company said the decision was made based on a review of available Pha...

Three or more cups of coffee daily halves mortality risk in patients with both HIV and HCV

Patients infected by both human immunodeficiency virus (HIV) and hepatitis C virus (HCV) are at specific risk of end-stage liver disease and greater risk of cardiovascular diseases and cancer. In addition, HIV infection accelerates the progression of chronic hepatitis C to fibrosis and development of cirrhosis and end-stage liver disease. In these HIV-HCV co-infected patients, drinking at least three cups of coffee each day halved the risk of all-cause mor

The Week in Review: September 8 – September 15, 2017

Friday, September 15, 2017 News Recap: President’s Report from HepCBC’s Annual General Meeting (AGM) HepCBC held its Annual General Meeting on September 12, 2017, and we are pleased to note that all the issues that we needed to address were covered.  Rosemary Plummer has stepped down as president after 2 GREAT YEARS of service, but the rest of the Board of Directors has been re-elected, and some very important changes to our Constitution and Bylaws ...

Women with HCV face low ovarian reserve, infertility, miscarriage

Women of child-bearing age with hepatitis C showed early signs of menopause, putting them at greater risk for infertility, gestational diabetes and miscarriage, according to a recently published study. Sustained virologic response positively impacted these outcomes. “We report that the relationship between HCV infection and reproductive status in women is much deeper and broader than previously thought, with profound consequences for reproductive function

How liver cancer develops

An international team of researchers headed up by UZH Professor Achim Weber from the Institute of Pathology and Molecular Pathology of the University Hospital Zurich and Mathias Heikenwälder, professor at the German Cancer Research Center in Heidelberg, Germany, has discovered a major mechanism in the development of liver cancer. One of the main players in this process is enzyme caspase-8, which assumes an important dual role. Liver cancer is the second...

The Week in Review: July 21 – July 28, 2017

Friday, July 28, 2017 News Recap WHD 2017 Victoria, BC in Pictures The weather was perfect; the organization and volunteers did great!!!!  The speakers were fabulous!! I only wish more people had shown up!!!  Big thanks to VPWAS and AVI for helping to make this important event a reality! Click on photos to see larger image in a new window! Should we be worried about hepatitis E? Hepatitis E virus infection (HEV) is the most common cause of a...

Compound Found in Plums Shown to Inhibit Hepatitis C Virus Entry

A naturally occurring compound in plums has been found to block the entry of the hepatitis C virus (HCV) into cultured liver cells. This finding could have positive implications for the development of new drugs to treat the disease, which the World Health Organizations (WHO) estimates affects over 70 million individuals around the world. The discovery was made by a team of researchers from the Indian Institute of Science in Bangalore focused on a flavon