Researchers find sofosbuvir effective in treating Zika-infected individuals

Researchers in California and Brazil said a drug meant to treat and cure hepatitis C could be as effective in treating people infected with Zika, especially in protecting the fetus of an infected pregnant women. Researchers associated with the University of California San Diego and colleagues in Brazil found that in cellular and mice trials, the anti-viral medication Sofosbuvir, brand name Sovaldi, was effective in repairing cells damaged by Zika and bl

The Week in Review: January 12 – January 19, 2018

Friday, January 19, 2018 News Recap: Research & Discoveries: Blood test for early detection of 8 cancers looks promising. Scientists have developed a blood test that can detect eight common cancer types through assessment of the levels of circulating proteins and mutations in cell-free DNA. The test, called CancerSEEK, clinically detected cancers of the ovary, liver, stomach, pancreas, esophagus, colorectum, lung, or breast. CancerSEEK tests wer...

Blood test for early detection of 8 cancers looks promising

Test includes some of the most deadly cancers currently lacking screening tools. Scientists are reporting progress on a blood test to detect many types of cancer at an early stage, including some of the most deadly ones that lack screening tools now. Many groups are working on liquid biopsy tests, which look for DNA and other things that tumours shed into blood, to try to find cancer before it spreads, when chances of a cure are best. In a study Thu

The Week in Review: December 15 – December 22, 2017

Friday, December 22, 2017 News Recap: Eight Genotypes: Did you know that there are now 8 genotypes and 84 subtypes of HCV that have been identified?  On the one hand this is terrible news; but on the other, a study presented at AASLD 2017 found that Vosevi was effective against them all.  Eight Genotypes and 84 Subtypes of HCV. Telemedicine: Did you know that Project ECHO (Extension for Community Health Outcomes), a fast-growing international tele...

Should uninfected patients accept hepatitis C-infected livers to reduce waiting time?

Study suggests that antiviral drugs may allow safe transplantation of HCV-positive livers into uninfected recipients. A modeling study by Massachusetts General Hospital (MGH) investigators finds that the availability of directly-acting antiviral (DAA) drugs to treat hepatitis C virus (HCV) infection could allow the transplantation of livers from HCV-positive donors into HCV-negative recipients without posing undue risk. The team's report will appear i

The Week in Review: December 1 – December 8, 2017

Friday, December 8, 2017 News Recap: URGENT BC Patient and Caregiver Input Request: Vosevi. We need to hear your voice! Patient and Caregiver input is requested by BC PharmaCare on Gilead’s combo of sofosbuvir, velpatasvir, and voxilaprevir (SOF-VEL-VOX or Vosevi™) for Genotypes 1-6. Personal Stories This week we have two great stories of triumphing over HepC: Aidain’s ‘I will never forget the day I found out I had hepatitis c’, and Patric...

A South American amphibian could potentially hold the key in curing cirrhosis

The unique liver function of a South American amphibian, Siphonops annulatus, could pave the way to finding a cure to the devastating liver condition cirrhosis, a new study published in the prestigious Journal of Anatomy reports. Researchers from the University of Surrey (UK), the Federal University of São Paulo and the Butantan Institute in Brazil used an innovative 3D liver cell examination to explore the liver function of this snake-like amphibian. Dur

The Week in Review: October 6 – October 13, 2017

Friday, October 13, 2017 News Recap: Research & Discoveries After an intense hunt, researchers at the Norwegian University of Science and Technology (NTNU) can now describe an important part of the disease's guerrilla tactics: how hepatitis C converts innocent cells into outright virus factories.  How hepatitis C hides in the body. Apparently, liver cancer can be caught at an early stage through a newly developed blood test, improving the odd...

How hepatitis C hides in the body

The Hepatitis C (HCV) virus is a sly enemy to have in one's body. Not only does it manage to make itself invisible to the immune system by breaking down communication between the immune cells, it also builds secret virus "factories" that quickly go into mass production. It takes one to three months from infection to disease, which in the worst case scenario can lead to liver failure and death over time. After an intense hunt, researchers at the Norwegi

Blood test may find liver cancer earlier, improve survival

Liver cancer can be caught at an early stage through a newly developed blood test, improving the odds for survival, according to a study led by University of California San Diego scientists. The test looks for changed gene activity, caused by a process called methylation, that indicate liver cancer, said Kang Zhang, M.D., the study’s senior author. Methylation turns genes on or off, but doesn’t affect the underlying DNA sequence. Early detection is imp