Gilead wins reversal of $2.54 bln hepatitis C drug patent verdict

Feb 17 (Reuters) - A federal judge in Delaware has overturned a jury’s verdict requiring Gilead Sciences Inc to pay a record $2.54 billion because its hepatitis C drugs Sovaldi and Harvoni infringed a patent held by rival Merck & Co Inc. The verdict had been the largest ever in a U.S. patent case but U.S. District Judge Leonard Stark in Wilmington, Delaware, on Friday ruled Merck’s patent was invalid. He said it did not meet a requirement that it disc

The Week in Review: January 19 – January 26, 2018

Friday, January 26, 2018 News Recap: Research and Discoveries: Growing Evidence Shows Hepatitis C Intersects With Other Diseases. As many as three-quarters of individuals with hepatitis C virus (HCV) experience disorders related to the virus beyond the impact on their livers, the National Viral Hepatitis Roundtable estimates. HCV-related kidney disease, depression, skin disorders, lymphoma and other conditions can seriously impact a patient, even wi...

Researchers find sofosbuvir effective in treating Zika-infected individuals

Researchers in California and Brazil said a drug meant to treat and cure hepatitis C could be as effective in treating people infected with Zika, especially in protecting the fetus of an infected pregnant women. Researchers associated with the University of California San Diego and colleagues in Brazil found that in cellular and mice trials, the anti-viral medication Sofosbuvir, brand name Sovaldi, was effective in repairing cells damaged by Zika and bl

The Week in Review: September 1 – September 8, 2017

Friday, September 8, 2017 News Recap: She thought her mystery ailment was cancer, but bloodwork revealed a surprise This is an amazing story ...but it could happen to anyone, and we know this because we hear these kinds of stories often. This is why it is so important that Boomers be tested for hepatitis C. Gail Wells got really sick and nobody could figure out why. They looked for cancer, for multiple sclerosis, for vitamin deficiencies, and then s...

HCV treatment found safe and effective in individuals with kidney disease

A new study indicates that direct-acting antiviral therapy is safe and effective in patients with chronic kidney disease (CKD) and Hepatitis C virus (HCV) infection. The study, which appears in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN), also found that treatment may help improve some patients' kidney function. HCV infection—which often causes liver disease—is common in patients with CKD, and it increases their

The Week in Review: June 2 – June 9, 2017

Friday, June 9, 2017 News Recap Somebody Pinch Me This week saw the release of a report from the Cochrane Collaboration which concluded not only that DAAs were ineffective but that they might also be bad for you and not even cure HCV.  The news item was picked up by various media outlets and was hard to miss (No valid evidence $40,000 miracle drug cures hepatitis C – study).  Thankfully other researchers from around the world jumped in on this poor ...

Sofosbuvir Reduces Transplant Need and Mortality Rates in Hepatitis C Patients, Study Finds

Sofosbuvir (sold under the brand name Sovaldi from Gilead Sciences, among others) significantly reduces the risk of death and the need for liver transplant in patients with hepatitis C who suffer from advanced stages of liver disease. Researchers at Intermountain Healthcare’s Intermountain Medical Center in Salt Lake City studied almost 1,900 patients with hepatitis C and found that the number of patients needing a liver transplant was reduced by 40 per...

The Week in Review: March 31, 2017 – April 7, 2017

Friday, April 7, 2017 News Recap Canada Effective April 2017, Alberta Health has expanded access to treatments for hepatitis C in line with what the provinces of British Columbia, Ontario, Saskatchewan, and Québec have just done (Alberta expands drug coverage for hepatitis C patients). As Dr. Shafran, who is clearly worried about continued restrictions, says, “The funders have now opened the doors to let us treat people with mild liver disease … if ...

U.S.: FDA approves two hepatitis C drugs for pediatric patients

The U.S. Food and Drug Administration today approved supplemental applications for Sovaldi (sofosbuvir) and Harvoni (ledipasvir and sofosbuvir) to treat hepatitis C virus (HCV) in children ages 12 to 17. Harvoni and Sovaldi were previously approved to treat HCV in adults. These are the first direct-acting antiviral treatments approved for children and adolescents with HCV. Direct-acting antiviral drugs reduce the amount of HCV in the body by preventing th

Scale Up of Hepatitis C Treatment Possible as Brazil Rejects Patent on Key Drug

Decision enables price reductions and scale-up of treatment that leads to cure in 95% of cases Rio de Janeiro, 31 March, 2017 – Treatment for hepatitis C using the key drug sofosbuvir could be vastly scaled up in Brazil after the decision by the National Agency of Health Surveillance (Anvisa) to reject a key patent application on the drug marketed by pharmaceutical corporation Gilead. The decision could pave the way to enable generic competition in Brazil